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Recommend a Supplement

In order to help you find a good product, we’ve researched & compared the best l-serine supplements on the market right now.

Top 10 L-Serine Products Compared

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1. Relentless Improvement L-Serine

Relentless Improvement L Serine

Specs and Overview

  • This product has 500mg of L-Serine per serving, and 60 capsules come in a bottle.
  • Other ingredients in these capsules include L-leucine and the vegetable capsule.
  • One to three capsules should be taken a day with meals
  • Women who are pregnant or nursing should consult a physician before taking this product.
Where to Get It

2. Montiff Pure L-Serine

Montiff Pure L Serine

Specs and Overview

  • 500mg of L-Serine per serving
  • 50 capsules per container
  • L-Serine is a non-essential amino acid synthesized from L-Glutamine. It is proteogenic and plays an important part in collagen for both skin and connective tissue.
Where to Get It

3. BulkSupplements Pure L-Serine Powder

BulkSupplements Pure L-Serine Powder

Specs and Overview

  • 2000mg L-Serine per serving
  • This product comes in a powder form that can be mixed in with water or juice. While this product does dissolve in water, it might take some time to do so.
  • It claims to be the purest state of L-Serine as it does not have any fillers.
  • It is lab tested for verification and a purity guarantee.
  • The foil sealed pouch is resealable.
Where to Get It

4. Micro Ingredients Pure L-Serine Powder

Micro Ingredients Pure L Serine Powder

Specs and Overview

  • 2000mg L-Serine per serving
  • This product comes in a 500g bag of powder. It claims to be the purest form.
  • It is vegan-friendly as it does not contain additives, fillers, preservatives, and it is also non-GMO, gluten-free, and does not contain artificial colors or flavors.
  • It also helps to produce serotonin to help with mental wellness.
  • Furthermore, it is supposed to be dissolved in water or juice.
Where to Get It

5. Doctor’s Best Phosphatidyl Serine

Doctor's Best Phosphatidyl Serine

Specs and Overview

  • 100mg of Phosphatidylserine per serving
  • This product comes with 120 capsules
  • One capsule should be taken three times a day with meals for the best effect.
  • Other ingredients include cellulose, modified cellulose, silicon dioxide, and magnesium stearate.
  • This product does contain soy, and it is otherwise vegetarian-friendly.
  • It claims not to contain any other ingredients than those mentioned.
  • It is also non-GMO and gluten-free.
Where to Get It

6. Nature’s Way Phosphatidyl Serine

Nature's Way Phosphatidyl Serine

Specs and Overview

  • 500mg of Phosphatidylserine Complex (100mg Phosphatidylserine)  per serving
  • This bottle contains 60 soft gels
  • The product claims to be carefully tested and produced to superior quality standards.
  • It is gluten-free and does not contain salt, sugar, yeast, wheat, corn, dairy, artificial colors, flavors, or preservatives.
  • One soft gel should be taken three times a day with meals for the first month, and then it should be taken twice a day after that.
  • The main ingredient is Phosphatidylserine complex with gelatin, glycerin, soybean oil, and purified water as the secondary ingredients.
Where to Get It

7. Swanson Ajipure L-Serine

Swanson Ajipure L-Serine

Specs and Overview

  • 500mg of Ajipure L-Serine per serving
  • The bottle of this product contains 60 vegetarian-friendly capsules that hold
  • Per GMP guidelines set forth by the FDA, most products are formulated for 24 months from the date of manufacture. Liquids and probiotics are formulated for 12 months.
  • The bottle does not specify whether or not it contains soy products.
Where to Get It

8. Now Foods Soy-free Phosphatidyl Serine

Now Foods Soy Free Phosphatidyl Serine

Specs and Overview

  • 150mg of Phosphatidylserine per serving
  • This product is soy free and helps with cognitive health.
  • It comes with 60 tablets in a bottle
  • It is vegetarian and vegan-friendly.
  • Other ingredients include cellulose, stearic acid, magnesium stearate, silica, croscarmellose sodium, and a vegetable coating.
  • It contains 4mg of Vitamin C, 50mg of Calcium, and 150mg of Phosphatidyl Serine.
  • This product is also gluten-free.
Where to Get It

9. Douglas Laboratories L-Serine

Douglas Laboratories - L-Serine

Specs and Overview

  • 500mg of L-Serine per serving
  • This bottle contains 60 capsules and supplies 500mg of the L-Serine amino acid.
  • It does not contain yeast, wheat, gluten, soy, milk or dairy, corn, sodium, sugar, starch, artificial coloring, artificial preservatives, or GMOs.
  • One capsule should be taken daily with meals.
  • Other ingredients include cellulose, gelatin, and vegetable stearate.
Where to Get It

10. Olympian Labs Phosphatidylserine Complex

Olympian Labs Soy Free Phosphatidylserine Complex

Specs and Overview

  • 100mg of Phosphatidylserine per serving
  • It is also allergen and soy-free and does not contain any GMOs.
  • Olympian Labs, Inc. claims all products are made with the highest of quality.
  • Women who are nursing or pregnant should consult a physician before taking this product. The same is said for people taking prescription medications.
  • There are 60 capsules in this package
  • One pill should be taken daily with a meal.
Where to Get It

Frequently Asked Questions About L-Serine Supplements

What is L-Serine?

Serine is a non-essential, meaning the body synthesizes it, and it is comprised of amino acids that come in two types: L-serine and D-serine. L-serine can be created from other amino acids including glycine and other protein metabolites. It is converted to D-serine in cells, which support the nervous system. Since L-serine is not involved in the synthesis of mammalian proteins, it is not classified as a “Generally Regarded as Safe” compound by the FDA. It was discovered about 150 years ago, but research has been limited as to how far an understanding can be gained on the use and effects of the supplement.

How Do I Take L-Serine?

More often than not, this supplement is taken in a pill form. It can come as a powder that can be mixed in with water or juice, though. It can also be given by a doctor as an injection, too.

A typical dose is 300mg per day. We recommend speaking with your doctor before taking any supplements to determine the right dosage for you.

While a deficiency of L-serine has not been determined as detrimental, taking supplements to enhance the numbers of it present in the body does help several functions, as mentioned previously. It can be found naturally in the following foods:

  • Egg whites
  • Whole eggs
  • Swiss cheese
  • Provolone cheese
  • Lima beans
  • Bacon
  • Turkey
  • Wheat germ
  • Quinoa
  • Venison
  • Avocado

How Do I Pick a Good L-Serine Product?

You need to make sure that quality is the focus of the product. As with other supplements, some companies will use fillers and additives to stretch the ingredients being used in L-Serine. Therefore, it is essential to look for high-quality ingredients.


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