Weight Loss Thermogenic Fat Burners

Top 10 Thermogenics for Weight Loss in 2022

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Whether you’re looking to lose a few pounds of stubborn fat or looking to completely transform your body, using a thermogenic supplement may help you in your journey.

10 Best Thermogenic Products

In order to help you find a good thermogenic, we’ve researched & compared the best thermogenic supplements on the market right now.

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1. Instant Knockout

Instant Knockout Fat Burner

Instant Knockout is one of the most popular weight loss supplements available. Originally formulated for mixed martial arts fighters, Instant Knockout contains a potent blend of all-natural ingredients that work together to help you with your goals.

What’s Good

  • Enjoy longer workouts – Increases your energy in the gym
  • 90 Day Guarantee – 3 Month Deal covered by the guarantee
  • Worldwide Shipping*
  • Used in MMA

Package Deals:

  • 1 month supply – 1 Box
  • 2 month supply – 2 Boxes + FREE Delivery (USA & UK)
  • 3 month supply – 3 Boxes + 1 FREE Box + FREE Delivery (Worldwide*) + Free T-Shirt + 90 DAY GUARANTEE

Ingredients: One serving contains:

  • 500mg Green Tea Extract
  • 100mg Cayenne Pepper
  • 100mg Green Coffee Bean
  • 1800mg glucomannan 
  • 6 more natural ingredients, including B vitamins, zinc, caffeine anhydrous, chromium, and piperine.

Who makes it: Instant Knockout is made by Roar Ambition, a UK-based supplement company. With a focus on all-natural ingredients, Roar Ambition currently makes two highly effective, highly successful products; Instant Knockout, and TestoFuel. This small but rapidly growing company is on the cutting edge of fitness science and based on the successes of their current products, we are thoroughly excited to see what they come up with next!

Bottom line: Overall, Instant Knockout is a thermogenic powerhouse. This simple, all-natural, highly potent formula gets to work fast.

Roar Ambition, the company behind the product, is so sure that you’re going to love Instant Knockout that they offer a 90-day money-back guarantee!

Note: Instant Knockout is ONLY available via the official website. You won’t be able to find it in stores or elsewhere online.

2. Cellucor Super HD

Cellucor Super Hd

Super HD is one of the strongest thermogenics available. This convenient, affordable, and effective supplement gets to work right away. It only requires 2 capsules a day, compared to 3-6+ with competing products.

What’s Good

  • Affordable
  • Very convenient with only 2 capsules per day
  • Made by Cellucor, one of the best supplement companies out there

Ingredients: One serving contains:

  • 250mg SuperHD ThermoSculpting blend, consisting of blue whiting, green tea extract, and dandelion root extract.
  • 250mg SuperHD Sensory Impact blend, consisting of tyrosine, yohimbe, cayenne, rhodiola root extract, and more.

Who makes it: Super HD is made by Cellucor. Based in Texas, Cellucor was founded in 2002 and has quickly grown into one of the largest and best companies in the industry. Today, they offer an impressive selection of health supplements, ranging from thermogenics to protein powders and beyond. While best known for their C4 product line, Cellucor offers it all. With several prestigious awards under their belt and a huge group of loyal customers and fans, it’s no secret that Cellucor is one of the best in the business!

3. Universal Nutrition Animal Cuts

Animal Cuts Universal Nutrition

Universal Nutrition Animal Cuts is a premium thermogenic supplement from one of the biggest and most trusted companies in the entire supplement industry. Animal Cuts contains a huge number of active ingredients, with 8 separate proprietary complexes to target various aspects of thermogenesis, energy, and metabolism. This is an advanced product with a huge number of ingredients. There are blends to address all the most important aspects of weight management. With that said, the lack of clear info on dosage amounts for each ingredient could be a downside for some people.

What’s Good

  • 750mg stimulant complex, with caffeine, kola nut, guarana, and more
  • 750mg metabolic complex, with green tea leaf extract, coffee bean extract, and more
  • 350mg thyroid complex, with L-tyrosine, olive leaf extract, and more
  • 800mg water-shedding complex, with dandelion root, uva ursi root, and more
  • 500mg nootropic complex, with DMAE, bacopa monnieri, and more
  • 300mg cortisol inhibiting complex, with ashwagandha root, magnolia bark extract, and more
  • 300mg CCK boosting complex, with cha-de-bugre, apple pectin, and more
  • 500mg bioavailability complex, with ginger root, cayenne and more
  • Comes in packs for convenient use
  • Trusted company
  • Proprietary blends, individual ingredient doses are not listed

Who Makes It: Animal Cuts is made by Universal Nutrition, one of the largest supplement companies in the industry. They have been in business since 1977 and have a long track record of offering high-quality, popular products.

4. EVLution Nutrition Trans4orm

Evlution Nutrition Trans4orm

EVLution Nutrition Trans4orm is a multistage thermogenic complex for increased fat-burning potential. With a ton of potent ingredients, you can count on this product to target the most important aspects of fat burning, helping you with your weight loss goals. It is a bit on the expensive side, but it’s well worth it.

What’s Good

  • Multistage blend targets multiple aspects of fat burning
  • Includes B vitamins

Ingredients: One serving contains:

  • 500mg green tea leaf extract
  • 500mg tyrosine
  • 175mg caffeine anhydrous
  • 20mg synephrine
  • Much more, with many powerful compounds and extracts, there’s really too much to list here!

Who makes it: Trans4orm is made by EVLution Nutrition, a new and up-and-coming company that’s been making waves in the supplement industry. Founded in 2013, EVL has exploded in popularity, going on to win several industry awards and build a loyal following of customers and fans. With an impressive performance out of the gate, we’re excited to see what EVL comes up with within the coming years!

5. RSP Nutrition QuadraLean

Rsp Nutrition Quadralean

QuadraLean Thermogenic is an advanced thermogenic blend from a trusted company. It offers a weight management blend, energy blend, neuro blend, and thermogenesis blend to address various aspects of weight loss. It also contains adequate dosages of each ingredient (as well as clearly listed amounts, rather than proprietary blends), so you can ensure you’re getting an effective dose of each included ingredient.

What’s Good

  • 500mg CLA
  • 500mg L-carnitine tartrate
  • 200mg natural caffeine from green tea
  • 300mg choline bitartrate
  • 50mg Alpha GPC
  • 25mg grains of paradise
  • 25mg cayenne pepper fruit extract
  • GMP Certified
  • Ingredients included at adequate and clinically studied dosages
  • Trusted manufacturer

Who Makes It: This product is made by RSP Nutrition, a trusted firm specializing in sports science supplements. Founded in 2008, RSP is committed to creating products that put a premium on performance. They are known for affordable but highly effective products and a focus on customer satisfaction.

6. Jacked Factory Burn-XT

Jacked Factory Burn Xt Thermogenic

Burn-XT is a best-selling thermogenic made by a good company. It features 5 active ingredients in a relatively simple but potent formula. The serving size is just 2 capsules, so it’s convenient to take on a regular basis. It’s also earned excellent reviews from customers and from industry experts alike.

What’s Good

  • 700mg acetyl-L-carnitine
  • 450mg green tea extract
  • 270mg caffeine anhydrous
  • 50mg cayenne pepper fruit extract
  • 5mg black pepper extract
  • Very high caffeine content
  • Made in a GMP Certified facility
  • Money-back guarantee
  • Best-seller on Amazon

Who Makes It: This product is made by Jacked Factory, a manufacturer of scientifically dosed, premium supplements. Jacked Factory focuses on products for bodybuilders and fitness enthusiasts. They offer high-quality products and back their offerings up with a money-back guarantee!

7. MuscleTech Hydroxycut Hardcore Elite

Hydroxycut Hardcore Elite

Hydroxycut Hardcore Elite is a powerful weight loss supplement from MuscleTech. This product uses a unique blend of ingredients to target the 3 most important pillars of fat burning: thermogenesis, metabolism, and energy. In one easy and convenient product, you’ll get tons of benefits and be well on your way to a new body!

What’s Good

  • Affordable
  • Convenient – small capsules

Ingredients: One serving contains:

  • 270mg caffeine anhydrous
  • 250mg coleus forskohlii
  • 200mg green coffee extract
  • 100mg L-theanine
  • 3mg yohimbe

Who makes it: This product is made by MuscleTech, one of the largest and most well-respected brands in the business. For years, MuscleTech has worked hard to develop cutting-edge products and maintain its reputation for quality and consistency. With more than 20 years of industry experience and a loyal following of fans, MuscleTech is a company you can trust.

8. Old School Labs Vintage Burn

Old School Labs Vintage Burn

Vintage Burn is a good thermogenic made by Old School Labs. Combining 9 powerful fat-burning ingredients. Using a potent blend of all-natural ingredients, with no preservatives, fillers, or synthetic junk, Vintage Burn is a clean and simple product.

What’s Good

  • Contains 9 weight loss ingredients
  • Includes raspberry ketones, green tea extract, and more
  • Third-party tested
  • Money-back guarantee
  • Zero artificial substances, additives, or preservatives

Ingredients: One serving contains:

  • 330mg green tea leaf extract
  • 270mg green coffee bean extract
  • 200mg raspberry ketones
  • 150mg caffeine
  • Other ingredients, including olive leaf extract, bacopa leaf extract, garcinia fruit extract, chrysin, and forskohlii root extract.

Who makes it: Vintage Burn is made by Old School Labs, a California-based manufacturer of fitness supplements. For more than 40 years, OSL has been focused on making “supplements that make sense”, using proven ingredients, clinically effective doses, and innovative formulas. Old School Labs is a company that truly puts its customers first.

9. MHP Thyro-Slim

Mhp Thyro Slim

Thyro-Slim is a unique fat-burning supplement made by MHP. Using two unique formulas, one designed for daytime use and the other for nighttime use (AM/PM), Thyro-Slim is an innovative product that aims to increase your fat-burning potential 24 hours a day. With a blend of tons of different herbal and natural ingredients, there’s a lot packed into this one product.

What’s Good

  • Unique dual product: AM and PM formulas
  • AM formula aims to increases energy
  • PM formula does not contain caffeine
  • Comes from a known company

Ingredients: One serving contains:

  • Thyrogenic (AM formula) contains thermogenic ingredients such as raspberry ketones, green tea extract, guarana seed extract, and more.
  • Thyrodrene (PM formula) contains a soothing herbal blend, cleansing blend, restoration blend, and thyrogenic blend, consisting of many herbal ingredients such as acai extract, uva ursi leaf, chamomile flower extract, and much more.

Who makes it: Thyro-Slim is made by MHP, otherwise known as Maximum Human Performance. Founded by pro bodybuilder Gerard Dente, MHP has used innovative formulas and unique approaches to formulate effective fitness supplements for many years now.

10. Genius Burn

Genius Brand Genius Burn

What’s Good

  • 9 Fat burning ingredients
  • Contains ingredients that target cognitive enhancement
  • Caffeine-Free
  • Vegetarian Capsules

Ingredients: One serving contains:

  • 150 mg of KSM 66 Ashwagandha extract
  • 100 mg of Cognizin (Citicholine)
  • 50 mg of Theacrine
  • Genius TruLean System-1
    • 25 mg of Paradoxine Aframomum meleguete (seed)
    • 10 mg of Lean GBB (Gamma-Butyrobetaine Ethyl Ester)
  • 12.5 mg of Capsimax Capsicum [Fruit] Extract
  • 50 mg of GS4 Plus Gymnema sylvestre (leaf)
  • 12.5 mg of AstraGin (panax notoginseng)(root) Extract and Astragalus membranaceus (root) extract
  • 2.5 mg of Huperzia serrata (Whole Plant)

Thermogenics FAQ

In this section, we’ll try and answer some of the most frequently asked questions people have about thermogenic supplements.

What is a Thermogenic?

In essence, thermogenics are a category of ergogenic supplements designed to increase metabolism.

The term thermogenic refers to the natural process of thermogenesis, which is the process of expending energy (calories) to produce heat and maintain bodily functions (1).

Thermogenesis is a normal process in every living mammal. A standard rate of thermogenesis will burn an average amount of calories, both during exercise (active) and rest (inactive) periods.

Generally, these supplements are made up of a variety of herbal supplements and other natural ingredients. They will often contain stimulants, such as caffeine, which help to increase metabolism and provide more energy.

The highest quality thermogenic products will provide a balanced blend of natural ingredients that will work together to help you burn more fat.

How do Thermogenics Work?

Essentially, thermogenics aim to increase the rate of thermogenesis in the body, which increases energy expenditure both during exercise and rest (2).

More energy expended = more calories burned – which, with proper nutrition and exercise, translates to more weight loss.

So, basically, these supplements are designed to help you burn more calories, regardless of the activity you’re doing, by increasing your metabolic rate.

Obviously, you will always burn more calories when you’re active.

What Are the Common Ingredients in Thermogenic Products?

Thermogenic supplements and other weight loss pills use blends of different fat-burning ingredients to achieve the desired results.

Let’s take a look at some of the common ingredients used in these products, and how they affect the body.

  • Stimulants – Stimulants are found in most diet pills and are widely considered to be some of the most important ingredients found in these supplements. Caffeine anhydrous, guarana extract, green tea extract, and green coffee extract are the most common stimulants used.
  • Thermogenic extracts & herbs – Many herbal extracts and natural compounds are used in these supplements for their positive effects on thermogenesis. These thermogenic ingredients are ones such as raspberry ketones, coleus forskohlii, etc. Capsaicin (an acid found in spicy peppers) is also often added for its ability to increase thermogenesis (3).
  • Appetite suppressants – Oftentimes appetite suppressants are added to these products to help you keep your diet in check.
  • Energizing ingredients – Most blends contain caffeine, which we talked about in the stimulants section. Some products also include other energizing ingredients, such as Panax ginseng (4), B-vitamins, and more.

What Are the Benefits of Thermogenics?

Each product uses a different formula, but the overall goal of these supplements is the same.


Thermogenesis is a natural metabolic process in which your body burns calories to produce heat (5).

Thermogenesis is a routine process in the body, but some supplements aim to increase the rate of thermogenesis in order to burn more calories.

Several included ingredients may help.

Cayenne pepper and capsaicin, common ingredients in thermogenics, can induce thermogenesis and promote fat oxidation (56).

Forskolin may also affect thermogenesis by activating cyclic AMP (7).

Stimulants, a common staple of thermogenics, help to increase thermogenesis in many people (8).

It’s important to note that many of these ingredients have a very mild effect on thermogenesis and are unlikely to have a major effect on caloric burn rates.

Still, in aggregate, they may be beneficial.


Thermogenic supplements are designed to support a healthy metabolism.

Some claim to increase the metabolic rate, thereby burning more calories. This is possible, but many claims are overblown.

With that said, there is some evidence to support certain ingredients used in thermogenics.

Caffeine can help to boost the metabolism and help you burn more fat. One study found that caffeine increased the energy expenditure rate (metabolism) by up to 16% over a 1-2 hour period (910).

It appears that caffeine from all sources has a similar effect, so there is little difference between taking a supplement containing caffeine and simply drinking a cup of coffee.

Green tea extract can also help. In addition to the benefits derived from caffeine, green tea extract contains the polyphenol epigallocatechin gallate (EGCG), which is beneficial for cardiovascular and metabolic health and may also help you burn more fat (1112).

One review of independent research studies found that a combination of catechin (found in green tea) rich tea and caffeine had an effect on fat oxidation. (13).

Weight Management

In addition to the various benefits discussed above (coming mostly from caffeine, green tea, and capsaicin), other ingredients have some potential for weight loss.

Garcinia cambogia may help to cause modest weight loss, primarily by helping to suppress the appetite and reducing the accumulation of some body fat in obese individuals (1415).

Other ingredients may be beneficial as well, but more research is needed.

It’s important to note that many potential benefits of thermogenics are not definitively proven by clinical science. There is also a lot of misinformation and hype marketing involved in the industry.

Lastly, no thermogenic will offer many benefits if you’re not also eating well and exercising regularly. In combination with a healthy diet and exercise plan, thermogenics might help you shed a bit more weight – but they are far from a magic weight loss solution.

Who Can Benefit from Thermogenics?

Anyone who would like to lose weight can benefit from adding a thermogenic supplement to their diet.

Here are the people who can benefit the most:

  • Men of all ages – Any man over 18 years of age who wants to drop a few pounds, or even lose a significant amount of weight, can benefit from a good thermogenic. Men tend to carry excess fat in their stomachs, leading to the dreaded “beer belly”. Whether you want to get rid of your beer belly or drop some pounds, a thermogenic may help.
  • Women of all ages – Women, too, can greatly benefit from thermogenics. Women naturally carry more body fat than men, often in their hips, butt, and stomach areas (16). Any woman over 18 who wants to shed some weight can do so with the help of a good supplement, proper diet, and exercise.
  • Athletes and weightlifters – Athletes, weightlifters, and fitness enthusiasts of all types can find benefits from taking thermogenics. Anyone who likes to stay in shape would likely appreciate the increased metabolism that comes hand in hand with these supplements. And especially for bodybuilders, who often have to consume large quantities of food in order to pack on muscle, thermogenics can be essential to help avoid gaining fat. These supplements are also highly useful during bulk and cut cycles.
  • Aging men and women – When we reach a certain age, our metabolisms begin to slow down. This is a completely natural process, and it’s unavoidable for most people. If you’ve noticed that your metabolism isn’t what it used to be, you may have to alter your diet in order to maintain your weight and stay in shape. Using a thermogenic may help keep you lean and defined by naturally increasing your metabolism.

Side Effects of Thermogenics

Before you begin taking any sort of supplement, you should be aware of any potential side effects.

The vast majority of supplements can have at least some sort of side effect – although it really depends on the individual person and product.

Every product contains different ingredients, and every person reacts differently to those ingredients.

With that being said, these are some of the most common side effects of thermogenic supplements:

  • Difficulty sleeping

Most thermogenics use stimulants in their formulas, as stimulants help to increase metabolism.

However, if taken later in the day, these stimulants (such as caffeine) can make it difficult to get to sleep at night.

To avoid this, simply do not take these supplements later than mid-afternoon.

Just think about it like coffee – you wouldn’t drink a cup of coffee after dinner, so you shouldn’t take a supplement that includes caffeine after dinner, either.

  • Dehydration

Dehydration can occur in people taking thermogenics for a few reasons.

These products aim to increase thermogenesis, which heats up the body and burns more calories – but can also lead to dehydration. Make sure you drink enough water and fluids while on these supplements.

In some cases, other side effects may occur. Again, it really depends on how your body reacts to the ingredients used.

More severe side effects can occur if you take too much of a product. Always follow the written instructions on the product packaging, and never consume more than the recommended dose of ANY supplement.

Note: We do not recommend taking any supplements featured on this website without speaking with a doctor first.

How Do I Pick a Good Thermogenic Product?

In order to find the right thermogenic for you, you should be aware of the key factors to look for when making a choice.

There are a lot of options out there, some good, some great, and some a complete waste of money!

We encourage you to read user reviews and be informed of the products you choose to use.

Here are some things to look for when making your purchase:

  • Ingredients – obviously, you should first look closely at the ingredients label. What’s in the product? Does it contain proven, clinically studied ingredients to aid fat loss? How much of each ingredient does it contain?
  • Brand reputation – who makes the product? Are they a trustworthy company? There are a lot of companies manufacturing these products, but the best thermogenics come from, well, the best companies! Our list above contains ONLY products from quality companies – but if you choose to do your own research, be wary.
  • Value for money – how much does it cost? While you shouldn’t necessarily look for the cheapest option, you should always compare costs to see the price per serving/per day. Keep in mind that if you want the fastest thermogenic you’ll be paying a bit more than average.
  • Caffeine content – most of these supplements contain caffeine, but you should be aware of how much caffeine is in each serving. There’s about 80-160mg of caffeine in a cup of black coffee, which is useful for comparing products (17).
  • The convenience of use – the majority of thermogenics will require you to take 2+ doses throughout the day. However, some products require 3 or 4+ doses each day, which can become a hassle.

Have more questions? Get in touch with us using our contact page.

How Did We Pick These Supplements?

Our core value at Top10Supps is transparency which is why we are open about how we pick the supplements that you just saw. You can read more about our supplement ranking methodology here.

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