Best Choline Supplements – Top 10 Brands for 2022

In order to help you find a good product, we’ve researched & narrowed down the best choline supplements on the market right now.

Top 10 Choline Products Compared

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1. Double Wood Supplements Alpha GPC Choline

Double Wood Supplements Alpha GPC Choline provides 600mg of choline per serving. The serving size is two tablets. The bottle contains 60 capsules.

Specs

• Provides 600mg of choline per serving
• Not suitable for vegetarians
• Contains fillers
• Made in the USA
• Good reviews

Who Makes It?

Double Wood Supplements are made in the U.S. All products are tested for purity. They are made with high-quality ingredients and all orders are shipped for free.

Bottom Line

This is an effective choline supplement made from Alpha GPC.  However it is not suitable for vegans and it contains fillers.

2. Nature’s Way Choline

Nature’s Way Choline provides 500mg of choline per serving. The serving size is one tablet. The bottle contains 100 capsules. This is one of the highest-rated choline supplements on the market.

Specs

• Provides 500mg of choline per serving
• Bitartrate form
• Suitable for vegans
• Great reviews
• Value for money

Who Makes It?

Nature’s Way was founded in 1968 and is based in Arizona. They were the first major U.S. dietary supplement manufacturer to be certified organic. The company uses the TRU-ID program to ensure the authenticity of all its herbal ingredients. Their green lid botanicals are certified, and all their dietary supplements are non-GMO.

Bottom Line

This is one of the more powerful choline supplements. Bitartrate is the simplest form of choline and therefore easy to absorb. It is also suitable for vegans and vegetarians. This supplement is high-quality and provides good value for money.

3. NOW Foods Choline and Inositol

NOW Foods Choline and Inositol provides 500mg of choline per serving. The serving size is one tablet. The bottle contains 100 capsules.

Specs

• Provides 500mg of choline per serving
• Contains inositol
• Pack of two
• Great value
• Good reviews

Who Makes It?

NOW Foods is a U.S.-based company founded in 1968. It is headquartered in Bloomingdale, Illinois. The company is committed to producing high-quality dietary supplements and maintaining environmental sustainability. Now Foods has won a number of national awards.

Bottom Line

This is a top choline supplement made by a very reputable company. It has a potent strength and has the added benefit of inositol which supports healthy circulation and balanced hormones. The double pack is great value for money.

4. Bulksupplements Pure Choline DL-Bitartrate Powder

Bulksupplements Pure Choline DL-Bitartrate Powder contains 100 grams of choline, which is around 133 servings.

Specs

• Provides 750mg of choline per serving
• Contains no additives
• Gluten-free
• Sugar-free
• Lab-tested for purity

Who Makes It?

Bulksupplements is located in Henderson, Nevada. The company supplies more than 400 ingredients to consumers and manufacturers of nutritional supplements. Each product is tested prior to distribution to ensure quality and safety.

Bottom Line

This is a great option if you want a bulk supply of choline powder to add to drinks ot to make your own capsules.

5. Thorne Research – Phosphatidyl Choline

Thorne Research – Phosphatidyl Choline provides 420mg of choline per serving. A serving is one tablet. The bottle contains 60 gelcaps.

Specs

• Provides 420mg of choline per serving
• Gluten-free
• Non-GMO
• Not suitable for vegetarians
• Contains no known allergens

Who Makes It?

Thorne Research produces a range of dietary supplements and at-home test kits. They have more than 40 products currently undergoing clinical trials around the world. They conduct clinical research in conjunction with Emory, Johns Hopkins, and Mayo Clinic among others.

Bottom Line

If you’re not vegetarian and you’re looking for a potent supplement, this product fits the bill.

6. Solgar Choline

Solgar Choline provides 350mg of choline per serving. The serving size is one tablet. The bottle contains 100 capsules.

Specs

• Provides 350mg of choline per serving
• Suitable for vegans
• Dairy-free
• Gluten-free
• Great value

Who Makes It?

Solgar has been making dietary supplements since 1947. As well as standard supplements, they also offer ranges of vegetarian and kosher products. Solgar retails its products worldwide.

Bottom Line

These are good choline pills, particularly if you are looking for a supplement that is organic, kosher, and suitable for vegetarians and vegans.

7. Jarrow Formulas CDP Choline

Jarrow Formulas CDP Choline provides 250mg of choline per serving. The serving size is one tablet. The bottle contains 120 capsules.

Specs

• Provides 250mg of choline per serving
• Stabilized CDP Choline
• Contains no sweetener
• Good reviews
• High price

Who Makes It?

Jarrow Formulas is based in Los Angeles, California. The company formulates and manufactures dietary supplements. Founded in 1977, Jarrow markets its products throughout the U.S., Canada, and Mexico.

Bottom Line

Another good choline supplement. Although it is made with high-quality ingredients, it is not as good value for money as some of the former brands.

8. Country Life Choline

Country Life Choline provides 1200mg of choline per serving. A serving is one tablet. The bottle contains 100 soft gels.

Specs

• Provides 1200mg of choline per serving
• Easy to swallow soft gels
• Gluten-free
• Not suitable for vegetarians or vegans
• Contains soy

Who Makes It?

Country Life pledges always to use certified Good Manufacturing Practices in the production of all its supplements. They maintain strict quality control and ensure that all of their products are gluten-free.

Bottom Line

This supplement is made with high standards and is gluten-free. It contains no known allergens and is offered at a good price, but it’s not suitable for vegans.

9. Douglas Laboratories – Choline Bitartrate

Douglas Laboratories – Choline Bitartrate provides 235mg of choline per serving. A serving size is one tablet. The bottle contains 100 capsules.

Specs

• Provides 235mg of choline per serving
• Gluten-free
• Contains no artificial colors, sweeteners, or flavoring
• Dairy-free
• Choline bitartrate

Who Makes It?

This product is made by Douglas Laboratories, which is based in Pittsburgh, PA. Douglas Laboratories is both Good Manufacturing Practices and National Sanitation Foundation registered. They have won a number of awards for their collaborative research.

Bottom Line

This is a good quality choline supplement made from Choline bitartrate, which is a simple form of choline and a very easy body to absorb. It is also good value for money.

10. Nested Naturals Choline Bitartrate

Nested Naturals Choline Bitartrate provides 550mg per serving. The serving size is two tablets. The bottle contains 90 vegan capsules.

Specs

• Provides 550mg per serving
• Suitable for vegans
• Gluten-free
• Contains no common allergens
• Contains fillers

Who Makes It?

Nested Naturals has its roots in Canada. The company is dedicated to formulating dietary supplements that put people and the planet first. They source the finest raw materials and test them rigorously for purity and safety.

Bottom Line

Nested Naturals offers a high-quality, good value supplement. Unfortunately, it contains fillers.

Frequently Asked Questions About Choline Supplements

What is Choline?

Choline is a vitamin-like essential nutrient. Getting enough choline in your daily diet can help to prevent high homocysteine levels in your blood. A high level of homocysteine is known to increase the risk of stroke, heart attack, cancer, and dementia.

Choline is an essential nutrient. Although the body is able to synthesize very small amounts of choline, it must be obtained from the diet to maintain healthy levels. Most of the choline in the human body is found in fat molecules called phospholipids.

Lecithin is a phospholipid and is the most abundant of all of them. The structure of every single cell in the human body is made up of this fatty substance. It is essential for the proper functioning of the brain and the nervous system.

Lecithin is also a vital component of the heart muscles and the endocrine glands, and it makes up more than half of the total fat in the liver. Over-activity of the nervous system or glands will use up stores of lecithin more quickly than it can be replaced. If this happens, you will be left feeling exhausted and irritable.

Lecithin also helps the brain by improving memory. It is also responsible for boosting the effects of vitamin E, keeping the skin soft, smooth and young-looking, keeping the heart muscles in tone and good circulation.

Cholesterol and fats obtained from the diet are transported, by lipoproteins, to the liver. There they are transformed into low-density lipoproteins and transported through the blood steams to tissues where they are needed. Choline is essential for this process. Without choline cholesterol and fat would just build up in the liver. Important choline sources include liver, fish, beans eggs, dairy products, and soy foods.

What Are the Uses & Benefits of Choline?

A choline supplement is often recommended for its numerous health benefits. Choline benefits include:

• DNA: Choline is involved in the process of fat absorption and the production of cell membrane structure. Insufficient choline prevents cells from maintaining their proper structure and transmitting signals. Choline is required for gene expression and to produce DNA. Combined with folate, choline is also involved in methyl group processes, which create genetic material throughout the body.
• Central nervous system: Choline is essential for healthy nerve functioning. It assists in brain development and growth. It is possible that choline can improve nerve signaling capacity and protect neuronal membranes. Choline is a precursor to the neurotransmitter acetylcholine, which is essential for healthy nerve and muscle function. Acetylcholine plays an important role in memory and learning. Sufficient choline is required to prevent poor concentration, poor memory, and mood swings.
• Liver function: Choline is required for the transportation of cholesterol and triglycerides from the liver. Insufficient choline can result in a build-up of lipids in the liver causing fatty liver disease.
• Inflammation: Preliminary research shows that choline has the ability to inhibit the body’s inflammatory response factors. More studies are needed.
• Alzheimer’s and Parkinson’s disease: Initial trials suggest that choline may help to improve the symptoms of people suffering from mild Alzheimer’s disease. It may also alleviate symptoms such as stiffness and trembling in the body’s extremities caused by Parkinson’s disease.
• Athletic performance: In a study published in the Journal of the International Society of Sports Nutrition, a single 600mg dose of choline take 90 minutes before a resistance workout increased athletic performance. More research is needed.
• Pregnancy: The body’s need for choline may increase during pregnancy. Studies have been conducted to examine the relationship between maternal choline levels and the risk of neural tube defects, however, the results were inconsistent. More research is needed.
• Stroke: Recent studies suggest that taking a supplement of citicoline (a choline derivative) may limit neurologic damage in stroke patients. More research is needed.

How Do I Take Choline?

There is no standard recommended choline dosage. Most nutritional experts agree on the following suggested choline supplement dosage:

• Adults: 425- 550mg
• Pregnant women: 450-550mg
• Breastfeeding women: 550mg

Are There Any Side Effects of Choline?

Choline is considered to be safe when taken orally in the manufacturer’s suggested amounts. High doses above 3.5 grams are considered to be possibly unsafe. Possible side effects include upset stomach, sweating, diarrhea, and vomiting.

You should not take a choline supplement if you are taking Atropine as it may interfere with the effectiveness of this medication.

How Do I Pick a Good Choline Product?

When you’re looking for a good choline supplement, choose one that contains CDP choline. This is also sometimes called Alpha GPC choline, or Citicoline. This is the most potent form of choline and provides the most health benefits.

You should also choose a choline supplement that is non-GMO, made with organic ingredients and contains no common allergens, artificial sweeteners, colors or flavors, or fillers.